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Plump, Firm, Tone & Hydrate

Polynucleotides

Polynucleotides are naturally derived molecules that work at a deep cellular level to repair, rejuvenate, and strengthen the skin. They help stimulate fibroblasts, the cells responsible for collagen and elastin production.

  • Boosts collagen and elastin production
  • Improves skin firmness and elasticity
  • Reduces fine lines and wrinkles
  • Deeply hydrates and revitalises the skin
  • Minimises sun damage and acne scars
  • Enhances overall skin texture and tone
  • Suitable for all skin types
PricingMaximise ResultsPolynucleotides Before & AfterFAQs

How much do Polynucleotides cost?

The cost of Polynucleotide treatment depends on the number of sessions required, the treatment area, and individual skin needs. Most patients need two – three polynucleotides treatments, spaced two to four weeks apart. Maintenance treatments are usually recommended every six to nine months.

Now available across all five Premier Laser & Skin Clinics and online for home use, Vitarin Polynucleotide treatments represent the latest breakthrough in skin regeneration. Unlike traditional dermal fillers, Vitarin works beneath the surface to deeply hydrate, stimulate collagen, and repair skin at a cellular level — offering visible, long-term improvements to texture, elasticity and radiance.

Ameela is another polynucleotide-based treatment offered at our clinics, available only through licensed medical professionals. If you are interested in Ameela, please contact the clinic directly to book, as it cannot be purchased online.

What Are Polynucleotides and How Do They Work?

Polynucleotides are naturally derived molecules that act as bio-stimulators, encouraging the skin to repair and regenerate. When injected, they trigger fibroblasts—the cells responsible for collagen and elastin production—leading to firmer, plumper, and more youthful skin over time.

The process is simple and minimally invasive. A series of small injections are placed into the skin, where the Polynucleotides get to work boosting hydration, improving elasticity, and reducing inflammation. Unlike traditional injectables that provide instant volume, Polynucleotides offer progressive, long-term improvements, with visible results appearing in the weeks following treatment.

Skin feels deeply hydrated from the first session, with full rejuvenation becoming noticeable over two to four weeks as collagen production increases. The result is healthier, stronger skin that looks naturally refreshed.

Who is Polynucleotide Treatment For?

This treatment is ideal for anyone looking to improve skin quality, texture, and elasticity. It is particularly beneficial for those who are 25+ with fine lines, sun damage, acne scars, or dull skin. Because Polynucleotides work to restore skin from within and boost collagen production that naturally declines once you turn 25 years old.  They are suitable for all skin types making them a great option for anyone seeking natural-looking results without the need for fillers or surgery.

Polynucleotides can be used on the eyes, face, neck, and décolletage, as well as areas where the skin has become thin, crepey, or lacking elasticity. The treatment is commonly recommended for individuals experiencing early signs of ageing, loss of volume, or post-inflammatory scarring from acne.

Now Available Online

We’re pleased to offer Vitarin polynucleotides for online purchase, allowing you to access this revolutionary treatment even more conveniently. All online orders include full aftercare guidance and eligibility screening to ensure safety and effectiveness.

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Vitarin vs. Ameela: What’s the Difference?

Both Vitarin and Ameela are advanced polynucleotide treatments, but they differ in delivery and access.

Feature Vitarin Ameela
Access Available online or in-clinic In-clinic only with a licensed doctor/injector
Use For full face, neck, eyes, hands Primarily around delicate areas like the eyes
Formulation Polydesoxyribonucleotide-based Similar base, formulated for high sensitivity
Booking Online and walk-in available Consultation-only, doctor-led
Ideal for All skin types seeking long-lasting rejuvenation Clients with severe volume loss or deeper concerns
Recovery time Minimal Minimal

How Many Treatments Are Needed?

For best results, most clients require two sessions spaced four weeks apart. The effects are long-lasting, with many patients enjoying improved skin texture and hydration for six to nine months. Maintenance treatments are recommended two-three times a year to keep skin looking refreshed.

What to Expect from the Treatment

A consultation with one of our expert practitioners will determine if Polynucleotides are right for you. The procedure itself takes around 30 to 45 minutes and involves a series of small injections placed beneath the skin. While some redness or mild swelling may occur, this typically subsides within 24 to 48 hours, allowing most clients to resume daily activities immediately. It’s common for patients to experience small, pea-sized bumps at the injection sites, which typically resolve on their own within 48–72 hours.

Unlike treatments that deliver instant volume, Polynucleotides work gradually, stimulating natural collagen production. The first noticeable improvement is increased hydration, followed by firmer, smoother skin over the following weeks. Full effects become visible within four weeks, with continued improvements as new collagen develops.

Why Choose Premier Laser & Skin Clinics?

With over 15 years of experience in advanced skin treatments, Premier Laser & Skin Clinics is a trusted name in aesthetic care. Our practitioners are among the UK’s top specialists in Polynucleotide injections, ensuring safe, effective, and tailored treatments for every client.

Book your consultation today and discover how Polynucleotides can transform your skin from within.

How to Maximise Your Results

To get the most from your treatment, it’s important to follow a simple aftercare routine. Avoid sun exposure for at least 48 hours, use SPF 50 daily, and keep your skin well-hydrated. Strong skincare ingredients like retinol or exfoliating acids should be avoided for a few days to allow the skin to recover fully. Also avoid exercise for 24 hours after your treatment.

For enhanced results, Polynucleotides can be combined with microneedling, which allows deeper penetration of the product and further boosts collagen stimulation. This combination is especially effective for treating acne scars, fine lines, and overall skin texture.

  • Deeper penetration for maximum collagen stimulation
  • Faster skin healing and renewal
  • Enhanced hydration and skin glow

Frequently Asked Questions

What do Polynucleotides do to the skin?

Polynucleotides help repair and regenerate the skin by stimulating collagen and elastin production, boosting hydration, and improving overall skin quality. They work at a cellular level, reducing fine lines, enhancing elasticity, and restoring a youthful glow.

Is Polynucleotide better than Anti-Wrinkle Injections?

Polynucleotides and anti-wrinkle injections do different things. Anti-wrinkle injections relaxes muscles to smooth wrinkles, while Polynucleotides heal and rejuvenate the skin by stimulating natural collagen production. If you want long-term skin improvement, Polynucleotides are a great option.

What is better, Profhilo or Polynucleotides?

Both treatments improve skin hydration and elasticity, but they work differently. Profhilo delivers intense hydration with hyaluronic acid, while Polynucleotides repair and regenerate the skin at a deeper level. If you need skin healing and repair, Polynucleotides may be the better choice.

Are Polynucleotides made from salmon sperm?

Yes, many Polynucleotide treatments are derived from purified and processed salmon DNA, which is bio-compatible with human skin and completely safe.

What are the side effects of Polynucleotides?

Side effects are minimal. Some people experience mild redness, swelling, or small bruises at the injection site, but these usually fade within a day or two.

Which celebs have Polynucleotides?

While many celebrities are believed to use Polynucleotide treatments for skin rejuvenation, they rarely disclose exact procedures. The treatment is growing in popularity among those looking for natural, non-surgical anti-ageing solutions.

What are the risks of Polynucleotides?

The risks are low when performed by a trained professional. The most common side effects are temporary redness or swelling, and allergic reactions are extremely rare.

How much does a salmon sperm facial cost?

A Polynucleotide treatment typically costs £275 per session, but prices vary depending on the clinic and treatment area.

Are Polynucleotides worth it?

Yes, if you’re looking for natural skin rejuvenation with long-term benefits. Polynucleotides improve hydration, elasticity, and collagen production, making skin look healthier and more youthful over time.

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